Progenetix - genomic copy number aberrations in cancer
Link to array raw data plotting
ENSEMBL data link
Cancer topographies
Cancer entities by ICD-O classification
array data GEO link
Subset specific data plots and information
Progenetix site home or specific Progenetix data link
publications containing chromosomal CGH data
ENSEMBL data link
arrayMap oncogenomic array info site
publications containing metaphase analysis data
publications containing genomic array data
Clinical groups
PubMed article link
Example: Regional genomic imbalances in subset 8982/3: Malignant myoepithelioma (19 cases)
The Progenetix database provides an overview of copy number
abnormalities in human cancer from
Comparative Genomic
Hybridization (CGH) experiments. As a curated database, it collects genomic gain/loss
information of individual cancer and leukemia cases, published in peer reviewed journals.
29290 cases from 969 publications: Progenetix is with
20345 chromosomal CGH and 9061 genomic array experiments
the largest public database for interpreted ("called") whole genome CGH profiles. The data
covers 364 distinct diagnostic entities as classified according to the
International Classification of Disease in Oncology (ICD-O 3).
Additionally, the website attempts to lists all publications referring to (a)CGH experiments.
Progenetix users are encouraged to submit their (a)CGH data. Database & software
are developed by the group of Michael
Baudis at the University of Zurich.
Baudis, M. 2007. Genomic imbalances in 5918 malignant epithelial tumors: An explorative meta-analysis of chromosomal CGH data.
BMC Cancer 7:226
[PDF]Baudis, M. 2006. Online database and bioinformatics toolbox to support data mining in cancer cytogenetics.
Biotechniques 40, no. 3: 296-272.
[PDF]Baudis, M, and ML Cleary. 2001. Progenetix.net: an online repository for molecular cytogenetic aberration data.
Bioinformatics 12, no. 17: 1228-1229.
[PDF]
These tools were developed for our research projects. You are welcome to
try them out, but there is only
sparse documentation. If more support and/or custom analysis
is needed, please contact
Michael Baudis
regarding a collaborative project.
